SchoolLib can be used to keep track of a book collection. It uses information from the Library of Congress and Amazon.com to retrieve bibliographic information about the book, so you do not have to type it all in. It can also be used to keep track of which books you have loaned out, e.g., to students.
SchoolLib can be ordered from HappyJack Software. If you are at the University of Wyoming and you would like to try it out, drop me a line.